OMiProbe (Optical Fibre Micro Probe) is an optical device that allows quantitative cellular processes studies, and carries the disruptive potential for diagnosis. The objective of the OMiProbe project is aligned with the strategic objective of the European Commission for achieving a competitive and sustainable future for Europe, and the fight against civilization illnesses. The Commission identifies the screening and early diagnosis as the primary elements of this campaign. Similarly, the World Health Organization/Europe lists primary prevention, early detection and research as the keys to developing an effective public health strategy. Our goal is to join that fight, and address precisely the need for minimally invasive, fast and efficient, low-cost and accurate detection and diagnosis devices.